Lumbar Medial Branch Block for Chronic Low Back Pain

Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks

Recruiting N/A Interventional Study
Pain, Chronic Facet Joint Pain Pain, Procedural Analgesia
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
40 (estimated)
Sponsor
University of Pittsburgh · Other
Who this trial is looking for

This trial is looking for adults with chronic low back pain who are planning to receive a specific injection for pain relief. Participants will help researchers understand how this treatment affects pain signals in the brain.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am over 18 years old
  • I have chronic low back pain that lasts at least 3 months
  • My low back pain is usually stronger than 3 out of 10
  • I am scheduled for a lumbar medial branch block at UPMC Pain Management
  • I can understand and complete study-related questionnaires
  • I am willing and able to receive phone calls about the study
  • I meet the cognitive function requirements

You may not be able to join if

  • I have had spine surgery in the area where the injection will be given
  • I have active worker's compensation or litigation claims
  • I started new pain or psychiatric treatments within the last 2 weeks
  • I am not fluent in English
  • I have an unstable health condition that might affect the study

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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Answer a few quick questions to see if you may meet the eligibility requirements.

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About This Trial

This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Scheduled for lumbar MBB in UPMC Pain Management clinics * Age \> 18 years old * Predominantly axial chronic low back pain at least 3 months on a daily basis * Must meet the minimum criteria for cognitive function using the PROMIS 2-item cognitive screener (\>3) * Low back pai…
Contacts

Maya L Maurer, BS

412-665-8052

mam708@pitt.edu

CONTACT

Benedict J Alter, MD, PhD

412-677-0575

alterbj@upmc.edu

CONTACT