Radical vs Local Excision for Rectal Cancer With Clinically Complete Remission
Recruiting
N/A
Interventional Study
Rectal Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 180 (estimated)
- Sponsor
- National Taiwan University Hospital · Other
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About This Trial
In the present project, the investigators plan to more accurately select the rectal cancer patients with pathological complete response (pCR) to preoperative concomitant chemoradiation therapy (CCRT), taking advantage of quantification of circulating tumor DNA (ctDNA) in addition to the current available diagnostic modalities, including CT, MRI, PET and colonoscopy. The patients with suspected pCR…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. rectal adenocarcinoma completed nCRT and the imaging studies showed no residual malignancy;
2. physical status is within American Society of Anesthesiology（ASA）class Ⅰ to Ⅲ;
3. the lesion side can be reached by the transanal local excision, generally within 6 cm above anal ve…
Contacts