COVID-19 Research in Malawi

COVID-19 Transmission and Morbidity in Malawi

Recruiting Observational Study
SARS CoV 2 Infection SARS CoV 2 Vaccination
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
5 – 75
Sex
Any
Study type
Observational
Participants needed
1,500 (estimated)
Sponsor
Boston University · Other
Who this trial is looking for

This trial is looking for people in Malawi who have COVID-19 or are close to someone who does. Participants will help researchers understand how infections and vaccines work in the community.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have COVID-19 symptoms and my infection is confirmed
  • I am aged 5 to 75 years
  • I plan to live in Blantyre for the next 6 months
  • I live with someone who has confirmed COVID-19
  • I have not had a COVID-19 vaccine in the last 3 months
  • I am willing to follow the study procedures and visits
  • I give my informed consent to participate

You may not be able to join if

  • I cannot stick to the visit schedule
  • Half or more of my household does not want to participate
  • I am pregnant
  • I use cotrimoxazole prophylaxis long-term
  • I have had two negative COVID-19 tests in a row after Month 1

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
SARS-CoV-2 transmission was expected to have a devastating impact in sub-Saharan African countries. Instead, morbidity and mortality rates in nearly the whole region are an order of magnitude lower than in Europe and the Americas. To identify what is different requires a better understanding of the underlying immunological substrate of the population, and how these factors affect susceptibility to…
Trial Locations
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Eligibility Criteria
Inclusion Criteria Index Cases 1. Presents with symptoms of COVID-19 and has infection confirmed through RT-PCR or a rapid antigen test; 2. Aged 5 years to 75 years and plans to live in Blantyre, in the catchment area of the target research health centers for the following 6 months; 3. Confirmed SA…
Contacts

Clarissa Valim, MD ScD

(617) 414-1260

cvalim@bu.edu

CONTACT

Aditi S Kothari, BDS MDSc MPH

(617) 358-2441

aditi@bu.edu

CONTACT