LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF

Recruiting Phase 3 Interventional Study
Pulmonary Hypertension
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 85
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
230 (estimated)
Sponsor
Tenax Therapeutics, Inc. · Industry
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About This Trial

This study will evaluate the efficacy of TNX-103 (oral levosimendan) compared with placebo in subjects with PH-HFpEF as measured by the change in 6-Minute Walk Distance (6 MWD; Day 1 to Week 12).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Men or women, greater than or equal to18 to 85 years of age. 2. NYHA Class II or III or NYHA class IV symptoms. 3. A diagnosis of World Health Organization (WHO) Group 2 PH-HFpEF with qualifying hemodynamics 4. Qualifying Baseline RHC. 5. Qualifying echocardiogram 6. Qualifyi…
Contacts

Kevin Crawford

19198552145

k.crawford@tenaxthera.com

CONTACT

Douglas Hay, PhD

19198552110

d.hay@tenaxthera.com

CONTACT