The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium
Recruiting
Phase 4
Interventional Study
Postoperative Delirium
Major Noncardiac Surgery
Postoperative Cognitive Dysfunction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 65 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 1,332 (estimated)
- Sponsor
- Medical University of Vienna · Other
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About This Trial
Patients over the age of 65 years are at increased risk for developing delirium after noncardiac surgeries, resulting in increased morbidity and mortality. The prevention of postoperative delirium has been classified as a public health priority. However, so far data regarding possible intraoperative interventions to reduce the incidence of postoperative delirium is very scarce. Due to the more rap…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Provide written informed consent
* ≥65 years of age
* Scheduled for elective major noncardiac surgery with estimated time of surgery ≥ 2 hours
Exclusion Criteria:
* Patients undergoing emergency surgery
* BMI \> 45 kg/m\^2
* History of diagnosed dementia
* Language, vision, …
Contacts