No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
8 – 12
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
150 (estimated)
Sponsor
Arkansas Children's Hospital Research Institute · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This is an 8 to14-week three-arm randomized controlled in children 8 to 12 years old.
The main purpose of the study is to evaluate if stevia has benefits for weight control and metabolic function relative to caloric sweeteners, and whether it provides benefits in this regard similar to water.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria
* Age 8-12 years
* Normal weight: BMI percentile ≥5th to \<85th
* Excessive weight: BMI percentile ≥ 85th and \<140% of the 95th percentile or BMI ≥35 to \<40 kg/m2
* Current consumption of sugar sweetened beverages (≥2 times /wk)
* Low consumption of non-nutritive sweeteners (≤ …
Inclusion Criteria
* Age 8-12 years
* Normal weight: BMI percentile ≥5th to \<85th
* Excessive weight: BMI percentile ≥ 85th and \<140% of the 95th percentile or BMI ≥35 to \<40 kg/m2
* Current consumption of sugar sweetened beverages (≥2 times /wk)
* Low consumption of non-nutritive sweeteners (≤ 3 time/wk)
* Willingness to consume experimental products Exclusion Criteria
* Children with class 3 obesity (i.e., BMI ≥ 140% of the 95th percentile or BMI ≥ 40.0 kg/m2)
* Dislike of experimental beverage taste (assessed at initial visit)
* Asthma that requires daily use of inhalers to keep symptoms under control.
* Asthma that requires use of rescue inhalers (e.g., albuterol) \>2 days per week
* Exercise induced asthma.
* Autism spectrum disorder (e.g., Autistic disorder, Rett disorder, Asperger disorder, childhood disintegrative disorder, pervasive developmental disorder not otherwise specified (PDD-NOS).
* Attention deficit hyperactivity disorder (ADHD) currently under medication.
* Oppositional defiant disorder (ODD).
* Epilepsy.
* Cancer.
* Chronic kidney disease.
* Endocrine disorder (e.g., hypothyroidism and growth hormone deficiency).
* Autoimmune diseases (e.g., lupus, thyroiditis, juvenile idiopathic arthritis)
* Bleeding disorders (e.g., hemophilia)
* Chronic infections (e.g., HIV, hepatitis B, hepatitis C).
* Mental health disorders (e.g., depression and anxiety).
* Type 2 and type 1 diabetes mellitus.
* Other pre-existing medical conditions or medications as determined by the investigators to affect the outcomes of interest.
* If, during the screening or consent process, the parent or child expresses refusal to have blood drawn. However, participants may remain in the study if after initially agreeing to the blood draw and enrolling they change their minds and choose not to allow blood draws or if blood draws are unsuccessful.
* Dislike of study products assessed at initial visit.
* Fasting glucose ≥126 mg/dl at enrollment.
* Fasting A1C ≥6.5% at enrollment
* Less than 2 months since completion of antibiotics
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.