Ketorolac or Triamcinolone for Thumb Arthritis

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis

Recruiting Phase 3 Interventional Study
Thumb Osteoarthritis
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
40 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
240 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for

This trial is looking for adults over 40 with thumb arthritis pain that hasn't improved with usual treatments. Participants will receive one of two types of injections to help relieve their symptoms.

Are You a Good Fit for This Trial?
Rules you out Inflammatory arthritisSevere hypertensionDe Quervain tendinopathyImmunodeficiency

You may be able to join if

  • I am over 40 years old
  • I have pain at the base of my thumb from pressure and movement
  • I have tried other treatments that didn't work
  • I have been diagnosed with thumb arthritis based on imaging
  • I understand the study and can give my consent
  • I have health insurance

You may not be able to join if

  • I am allergic to either treatment
  • I have changed my pain management plan in the last 4 weeks
  • I have another type of arthritis affecting my wrist
  • I have an infection
  • I have had surgery on my thumb
  • I have had an injury to my thumb
  • I have uncontrolled diabetes
  • I am pregnant or breastfeeding

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis. One injection is ketorolac (an NSAID) and the other is triamcinolone (a corticosteroid).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adults \>40 years of age * Pain at the thumb base brought on by direct pressure (grind test) and with movement * Pain resistant to previous conservative management (including over the counter medications (ibuprofen/acetaminophen), icing, splinting/braces, or topical analgesics…
Contacts

Lindsey Hobbs

5072939765

hobbs.lindsey@mayo.edu

CONTACT