CEST in Low-grade Glioma Study
Recruiting
N/A
Interventional Study
Low-grade Glioma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 12 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 100 (estimated)
- Sponsor
- Sunnybrook Health Sciences Centre · Other
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About This Trial
Low grade gliomas (LGGs) are malignant, infiltrative and incurable brain tumours that typically present in the younger population. This project proposes to use non-contrast metabolic "Saturation Transfer" (ST)-MRI to evaluate LGG tumour progression and aims to predict early changes in LGG. Early identification of LGG patients whose tumours will progress will permit early interventions. ST-MRI does…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Be at least 12 years of age;
2. Diagnosed with:
1. Cohort A (pre-surgical): Suspected LGG (oligodendroglioma or astrocytoma), based on any combination of histological, molecular, radiological, and/or clinical findings; or
2. Cohort B (post-surgical): IDH1/2-mutant or I…
Contacts