Attentional Mechanisms in SCD
Recruiting
Early Phase 1
Interventional Study
Subjective Cognitive Decline
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 55 and older
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 80 (estimated)
- Sponsor
- Vanderbilt University Medical Center · Other
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About This Trial
This study will use an anticholinergic pharmacological probe to examine attention network function in SCD using EEG. The overall hypothesis is that in older adults with SCD, normal cognitive performance is maintained by compensatory attention network activity, supported by enhanced cholinergic function. The investigators anticipate that SCD will be associated with greater compensatory attention ne…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. age ≥ 55
2. Montreal Cognitive Assessment (MoCA) \> 25 AND Global Deterioration Scale (GDS) rating \< 3
3. Non-smokers
Exclusion Criteria:
1. medical contraindications to the drug challenge
2. primary neurological disorder (such as stroke, epilepsy, etc.)
Contacts