Peripheral Nerve Stimulation for Chronic Knee Pain
Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
45 (estimated)
Sponsor
M.D. Anderson Cancer Center · Other
Who this trial is looking for
This trial is looking for adults with chronic knee pain to see how different treatments affect knee movement. Participants may receive a standard steroid injection, a combination of peripheral nerve stimulation and a steroid injection, or peripheral nerve stimulation with a placebo injection.
Are You a Good Fit for This Trial?
You may be able to join if
I have chronic knee pain with a pain score of 4 or higher.
I am between 18 and 85 years old.
I have given my consent to participate.
You may not be able to join if
I have cognitive dysfunction or cannot give consent.
I have abused drugs or alcohol in the past 6 months.
I have an open skin lesion or am on antibiotics for an infection.
I am allergic to local anesthesia, steroids, or adhesives.
I am taking opioids for reasons other than knee pain.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain:
* A standard steroid injection
* Peripheral nerve stimulation (PNS) therapy in combination with a standard steroid injection
* PNS therapy in combination with a placebo injection
Steroid injections are given directly into the knee joints and are considered to be the sta…
To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain:
* A standard steroid injection
* Peripheral nerve stimulation (PNS) therapy in combination with a standard steroid injection
* PNS therapy in combination with a placebo injection
Steroid injections are given directly into the knee joints and are considered to be the standard therapy for chronic knee pain. In this study, the injection will be made of the steroid drugs triamcinolone and bupivacaine.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Patients diagnosed with chronic knee pain (baseline pain score \>=4), seen at Pain Management Center at MD Anderson Cancer Center; if patient has bilateral knee pain, the side with the more severe knee pain will be treated first and counted towards the primary and secondary en…
Inclusion Criteria:
* Patients diagnosed with chronic knee pain (baseline pain score \>=4), seen at Pain Management Center at MD Anderson Cancer Center; if patient has bilateral knee pain, the side with the more severe knee pain will be treated first and counted towards the primary and secondary endpoints
* Patients between ages 18-85 years old
* Patient signed informed consent
Exclusion Criteria:
* Patients with cognitive dysfunction or without capacity to consent
* Patient with recent history (\<6 months) of drug or alcohol abuse
* Patients with open skin lesion or undergoing antibiotic therapy for local for systemic infection
* Patients with allergies to local anesthesia, steroids, or adhesives
* Patients who are on opioids for reasons other than knee pain
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.
