Study on Fitness, Mouth Bacteria, and Muscle Blood Flow
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
Recruiting
Observational Study
Heart Failure, Systolic
Heart Failure, Diastolic
Peripheral Arterial Disease
Overweight and Obesity
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 70 (estimated)
- Sponsor
- University of Virginia · Other
Who this trial is looking for
This trial is looking for people to help understand how fitness, bacteria in the mouth, and blood flow to muscles are related. Participants will provide saliva samples, do exercise tests, and wear a device to monitor blood pressure.
Are You a Good Fit for This Trial?
You may be able to join if
- I can communicate meaningfully with the study team.
- I am 18 years old or older.
You may not be able to join if
- I have used oral antibiotics in the last four weeks.
- I have poor oral health.
- I use antibacterial mouthwash and can't stop.
- I am a tobacco smoker.
- I am pregnant or breastfeeding.
- I am allergic to ultrasound contrast agents.
- I can't perform exercise.
- I can't communicate effectively in English.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The purpose of the study is to determine associations between fitness status, bacteria in the mouth, and the blood flow to muscle. This study is trying to find out if fitness status impacts the bacteria that are present in the oral microbiome (environment in the mouth) or the ability of the body to send blood to the skeletal muscle.
Participants will complete all or some of the following:
* A mo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Subjects must be able to communicate meaningfully with the investigator and must be legally competent to provide written informed consent.
* Subjects may be of either sex with age 18 years.
Exclusion Criteria:
* Oral antibiotic use within previous four weeks
* Oral disease o…
Contacts