Prognostic Prediction Model of Patients With AcUte Stroke undeRgoing EndOvascular TheRApy (AURORA)

Inclusion Criteria: * Age ≥18 years; * NIHSS score ≥4; * Image-confirmed (CTA/MRA/DSA) intracranial large artery occlusion; * ASPECT (anterior circulation) or PC-ASPECT (posterior circulation) score ≥3; * Endovascular treatment including arterial thrombolysis, mechanical thrombolysis, and angioplasty (onset to puncture time is recommended to be less than 8 hours for anterior circulation and less than 12 hours for posterior circulation; those exceeding the time window will be determined by the neurointerventionalist through imaging assessment); * Signed informed consent by the patient or legal representative Exclusion Criteria: * Pre-stroke mRS score \>2; * Intracranial bleeding disorders: cerebral hemorrhage, subarachnoid hemorrhage, etc.; * presence of coagulation disorders, history of systemic bleeding, history of thrombocytopenia or neutropenia; * Renal insufficiency with elevated blood creatinine (greater than 2 times the upper limit of normal); * Presence of severe cardiopulmonary disease that, in the opinion of the investigator, makes participation in this study unsuitable; patients with a life expectancy of less than 3 months or otherwise unable to complete this study; * Contraindication to DSA examination, severe contrast allergy or absolute contraindication to iodine contrast; women of childbearing age who have a negative pregnancy test but refuse to use effective contraception, are pregnant or breast feeding; * Those who are unable to complete the study due to psychiatric disorders, cognitive or mood disorders; * Other patients who, in the opinion of the investigator, are not suitable for enrollment in the study (specify reason).