Deep Brain Stimulation for Parkinson's Disease

Personalized Real-Time DBS and PD Mechanisms

Recruiting Phase 4 Interventional Study
Parkinson Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 80
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Basic Science
Participants needed
25 (estimated)
Sponsor
David Escobar · Other
Who this trial is looking for

This trial is looking for people with Parkinson's disease who are scheduled to have deep brain stimulation (DBS) surgery. Participants will help researchers understand how brain activity affects motor symptoms and how treatment can be customized in real-time.

Are You a Good Fit for This Trial?

You may be able to join if

  • I can provide informed consent.
  • I have been diagnosed with Parkinson's disease.
  • I am a candidate for DBS surgery targeting the subthalamic nucleus.
  • I can tolerate delays in taking my Parkinson's medication.

You may not be able to join if

  • I have secondary Parkinsonism, stroke, or another progressive brain disease.
  • I have a condition that might interfere with my safety or compliance in the study.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
A prospective cohort of patients scheduled to undergo deep brain stimulation (DBS) implantation surgery for the treatment of Parkinson's disease as per standard of care will be invited to participate in this study. This mechanistic study is aimed at better understanding the role of basal ganglia beta band (11-35 Hz) oscillations and resonance in the manifestation of Parkinson's disease (PD) motor …
Trial Locations
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Eligibility Criteria
Key Inclusion Criteria: * Ability to provide informed consent. * Clinical diagnosis of idiopathic Parkinson's disease. * Determined, as per standard of care, to be a candidate for deep brain stimulation (DBS) surgery targeting the subthalamic nucleus. * Ability to tolerate delays in taking daily st…
Contacts

David Escobar, PhD

216-390-1907

escobad2@ccf.org

CONTACT

Jeffrey Negrey, MA

216-316-6896

negreyj2@ccf.org

CONTACT