Standard Dose Continuous Renal Replacement Therapy (CRRT) Versus Low-Dose CRRT ( KETZEREI )
Recruiting
N/A
Interventional Study
Critical Illness
Acute Kidney Injury
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Supportive Care
- Participants needed
- 165 (estimated)
- Sponsor
- Universität Münster · Other
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About This Trial
Acute kidney injury (AKI) is a well-recognized complication in critically ill patients, which often leads to the necessity of mechanical kidney support (CRRT).
In current therapeutic regimes, CRRT is used to strictly prevent azotaemia. Thus recent clinical observations, as well as data from animal testing suggest a link between controlled azotaemia and faster renal recovery in AKI patients.
The …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adult patients (age ≥18 years)
* Critically ill patients with AKI + in need of CRRT
* Written informed consent
Exclusion Criteria:
* Chronic dialysis dependency
* Chronic kidney disease with estimated glomerular filtration rate (eGFR) \<30 ml/min/1.73m²
* severe liver cirrho…
Contacts