SMART Exercise for PAD

Recruiting Phase 3 Interventional Study
Peripheral Arterial Disease Aging Peripheral Vascular Diseases Walking, Difficulty
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
50 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
210 (estimated)
Sponsor
Northwestern University · Other
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About This Trial
Supervised exercise therapy (SET), consisting of treadmill exercise conducted three times weekly at a center while supervised by healthcare personnel, is first line therapy for people disabled by lower extremity peripheral artery disease (PAD). However, travelling three times/week to a center for SET is burdensome. Compared to SET, home-based exercise is more accessible and less burdensome. Yet, e…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: First, all participants will be age 50 and older. Second, all participants will have PAD. PAD will be defined as either: 1. An ABI \<= 0.90 at baseline. 2. Vascular lab evidence of PAD (such as a toe brachial pressure less than or equal to 0.70 or an ankle brachial index less t…
Contacts

Mary McDermott, MD

312-503-6438

mdm608@northwestern.edu

CONTACT