Establishment of a Primary Epididymal Cell Model From Epididymal Samples to Study CFTR Gene Regulation

Recruiting Observational Study
Cystic Fibrosis Congenital Bilateral Absence of Vas Deferens Sterility, Male
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Male
Study type
Observational
Participants needed
20 (estimated)
Sponsor
University Hospital, Brest · Other
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About This Trial
The aim of this observational study is to better understand the role and involvement of the regulatory elements of the CFTR gene, with the aim of better describing the 3D organisation of chromatin at the CFTR locus in epididymal cells in patients with male infertility of any kind, or with cystic fibrosis or bilateral agenesis of the vas deferens, requiring scheduled surgery. The main questions it…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Male patients over 18 years of age * Patients, without genetic pathology, scheduled for epididymal sampling surgery * Patients with cystic fibrosis or bilateral vas deferens agenesis, scheduled for epididymal sampling surgery. * Signature of a consent form Exclusion Criteria:…
Contacts

Antoine VALERI, MD,PhD

+33298347170

Antoine.Valeri@univ-brest.fr

CONTACT

Stéphanie MOISAN, PhD

+332 98 01 65 67

stephanie.moisan@chu-brest.fr

CONTACT