Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.
Recruiting
N/A
Interventional Study
Meconium Obstruction of Prematurity
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 1 Day – 36 Weeks
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 95 (estimated)
- Sponsor
- KK Women's and Children's Hospital · Government
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About This Trial
The goal of this clinical trial is to study the effect of twice-daily saline enema (SE) in the treatment obstruction of prematurity (MOP) in infants with the birth weight ≤1.25kg. The main questions, the trial aims to answer are
1. To validate the finding of our pilot study which had shown that twice-daily SE reduces the time to reach full enteral feeds in premature infant as compared to prematur…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Criteria A: For infant presenting with early onset of MOP
1. Birth weight 500 - 1250 gram
2. ≥ 23 weeks gestation
3. No BO for 48 hours
4. BO present but with a small amount or stain of meconium
5. Feeds intolerance or abdominal X-ray showing dilated loops of bowel
…
Contacts