Essential Amino Acid Supplementation for Femoral Fragility Fractures

Recruiting Phase 2 Interventional Study
Femoral Fracture Fragility Fracture Muscle Atrophy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
65 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Supportive Care
Participants needed
60 (estimated)
Sponsor
Michael C Willey · Other
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About This Trial
This trial will evaluate the impact of 4 weeks of postoperative essential amino acid (EAA)-based supplementation on muscle morphology after femoral fragility fracture. This trial will assess the ability of EAA-based to increase skeletal muscle metabolic activity, reduce inflammation, and induce muscle fiber hypertrophy, as well as preserve skeletal muscle mass and physical performance up to 6 mont…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Hospital inpatient * Age ≥ 65 years old on admission * Low-energy mechanism of injury * Diagnosis of femur fracture (OTA 31, 32, or 33 fracture) * Indicated for surgical fixation * Able to provide informed consent Exclusion Criteria: * Part of a vulnerable population (ex: In…
Contacts

Michael C Willey, MD

319-384-8452

michael-willey@uiowa.edu

CONTACT

Ashley S Kochuyt, BS

319-929-3559

ashley-kochuyt@uiowa.edu

CONTACT