Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients With Psychiatric Disorders and Comorbid Insomnia

Recruiting Phase 2 Phase 3 Interventional Study
Psychiatric Disorders Insomnia
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
16 – 64
Sex
Any
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Treatment
Participants needed
255 (estimated)
Sponsor
Lone Baandrup · Other
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About This Trial
The goal of this investigator-initiated, randomized, blinded, 3-armed placebo-controlled, pragmatic, clinical superiority trial is to examine the efficacy of melatonin or low-dose quetiapine versus placebo for treatment of insomnia in patients with psychiatric disorders. The aims of the study are: * To examine the efficacy of melatonin or low-dose quetiapine versus placebo for treatment of insomn…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * 16 to 64 years of age * ICD-10 diagnosis of a current or previous mental or behavioral disorder (F20-F69, F84, F90-95) * For the diagnoses F84 and F90 a previous period of treatment with melatonin is required * For the 16-17 years old: Non-pharmacological treatment options inc…
Contacts

Lone Baandrup, MD

+4591165903

lone.baandrup@regionh.dk

CONTACT