Ketone Ester Supplement for Type 2 Diabetes

Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function

Recruiting N/A Interventional Study
Type 2 Diabetes Ketone Body Metabolism Ketones, Metabolism
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 80
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
30 (estimated)
Sponsor
Ohio State University · Other
Who this trial is looking for

This trial is looking for adults with type 2 diabetes to see how a ketone ester supplement affects heart function. Participants will take the supplement or a placebo and undergo exercise testing.

Are You a Good Fit for This Trial?
Rules you out Type 1 diabetesSevere kidney diseaseOxygen-dependent pulmonary disease

You may be able to join if

  • I am between 18 and 80 years old.
  • I have been diagnosed with type 2 diabetes.
  • I have stable medical therapy for at least 1 month.
  • My BMI is 25 or higher.
  • I can participate in exercise testing.
  • I can sign written consent.

You may not be able to join if

  • I am pregnant, breastfeeding, or planning to become pregnant.
  • I have a pacemaker or other cardiac device.
  • I have severe kidney disease.
  • I have a history of diabetic ketoacidosis.
  • I had major surgery in the last 90 days.
  • I have active cancer or a recent cancer diagnosis.
  • I cannot follow the supplement guidelines.
  • I refuse to consent.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

This study is being done to evaluate how a ketone ester (KE) supplement affects heart function and health in people with diabetes compared to a placebo supplement (made with standard food ingredients that do not contain ketone esters).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age ≥ 18 years old and ≤ 80 years old 2. Type II Diabetes Mellitus 3. Stable medical therapy for at least 1 months as determined by the treating physician (no plan to change between the two testing sessions) 4. Dose of oral diuretics changes allowed, but must be stable for 1 …
Contacts

Debbie Scandling, BS

614-688-5623

debbie.scandling@osumc.edu

CONTACT

Christopher Crabtree, MS

crabtree.223@osu.edu

CONTACT