Effect and Mechanism of Brain Stimulation for Parkinson's Disease With Cognitive Impairment
Recruiting
Observational Study
Parkinson Disease
Cognitive Impairment
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- Up to 75
- Sex
- Any
- Study type
- Observational
- Participants needed
- 200 (estimated)
- Sponsor
- Tianjin Huanhu Hospital · Other
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About This Trial
This study intends to apply structural and functional brain network neuroimaging techniques combined with image post-processing methods to explore the differences in brain network changes in PD patients with cognitive impairment after DBS or TMS.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1\. The clinical diagnosis of PD is consistent with the United Kingdom Parkinson's Disease Society Brain Bank criteria, with disease duration over 5 years, acute levodopa motor response ≥30%, and indication for STN-DBS.
Exclusion Criteria:
Exclusion criteria included patients …
Contacts