Erythrocyte Transport of Lactate During Exercise (TELE Project)
Recruiting
N/AInterventional Study
Energy Metabolism
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 30
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
84 (estimated)
Sponsor
Technical University of Madrid · Other
Who this trial is looking for
This trial is looking for people to study how lactate moves in the blood during exercise. Participants will perform exercise tests and their blood will be analyzed.
Are You a Good Fit for This Trial?
You may be able to join if
I have a BMI between 18 and 25.
I do not smoke.
I train at least 5 hours a week, with 3 hours of endurance training.
I have a medical certificate for intense exercise.
I train less than 1 day a week or less than 2 hours of structured exercise.
You may not be able to join if
I have a health issue that could affect the tests.
I have irregular menstrual cycles.
I have oligomenorrhea.
I have amenorrhea.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The goals of this clinical trial are:
1. to study lactate kinetic between plasma and erythrocytes during an intervallic exercise and its subsequent recovery, considering the blood pH, the genotype for the T1470A polymorphism of the SLC16A1 gene (rs1049434), and the amount of MCT1 in erythrocytes membrane;
2. to analyze the levels of MCT1 in the erythrocytes membrane according to training status a…
The goals of this clinical trial are:
1. to study lactate kinetic between plasma and erythrocytes during an intervallic exercise and its subsequent recovery, considering the blood pH, the genotype for the T1470A polymorphism of the SLC16A1 gene (rs1049434), and the amount of MCT1 in erythrocytes membrane;
2. to analyze the levels of MCT1 in the erythrocytes membrane according to training status and genotype for the T1470A polymorphism of SLC16A1 (rs1049434).
For this, the project will have two phases:
* In phase I, trained participants will perform one maximal incremental test and one intervallic submaximal test with a final active recovery.
* Phase II, levels of the MCT1 protein in the erythrocyte membrane will be quantified from trained and sedentary participants.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* BMI between 18 and 25 kg/m2
* Not smoker
* In the case of trained participants: training at least 5 hours/week, of which at least 3 must be aerobic/anaerobic endurance training. Presentation of a medical certificate attesting to their medical fitness (capability) to perform in…
Inclusion Criteria:
* BMI between 18 and 25 kg/m2
* Not smoker
* In the case of trained participants: training at least 5 hours/week, of which at least 3 must be aerobic/anaerobic endurance training. Presentation of a medical certificate attesting to their medical fitness (capability) to perform intense physical exercise.
* In the case of sedentary participants, less than 1 day of training per week or less than 2 hours of structured exercise per week.
Exclusion Criteria:
* Presenting any pathology that could impede the correct performance of the tests, or could influence the main study variables.
* In the case of the female sample, having irregular menstrual cycles, oligomenorrhea or amenorrhea.
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