The Effect of ACT and Tranexamic Acid on Bleeding in Cardiac Surgery
Recruiting
Phase 4
Interventional Study
Surgery, Cardiac
Tranxemic Acid
Activated Clotting Time
Heparin
Cardiopulmonary Bypass
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 150 (estimated)
- Sponsor
- Taichung Veterans General Hospital · Other
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About This Trial
The goal of this clinical trial is to the dose effect of tranexamic acid and the level of ACT on bleeding in adult cardiac surgery.
The main questions it aims to answer are:
1. Does higher dose of tranexamic acid reduce the amount of bleeding and blood transfusion?
2. Does lower ACT level during cardiac surgery reduce the amount of bleeding and blood transfusion?
Participants will divided into …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* adult, cardiac surgery with cardiopulmonary bypass
Exclusion Criteria:
* pregnant
* emergency procedure
* immune compromised
* aortic surgery
* end-stage renal disease
* liver disease
* critical status
* incomplete clinical data
Contacts