Endothelial Damage in Major Spine Surgery, Measured by Circulating Syndecan-1: an Observational Study.(GlycOrtho)
Recruiting
Observational Study
Spinal Fusion
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 12 – 75
- Sex
- Any
- Study type
- Observational
- Participants needed
- 30 (estimated)
- Sponsor
- Istituto Ortopedico Rizzoli · Other
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About This Trial
The goal of this observational study is to learn about endothelial damage in major spine surgery, expressed as rise in circulating Syndecan-1.
The main questions it aims to answer are:
* What is the extent of endothelial glycocalyx shedding in major spine surgery?
* Are there differences in different type of surgical populations? (adolescent idiopathic scoliosis, adult degenerative spine disease…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Undergoing Major Spine Surgery with estimated blood loss\> 25% of total blood volume
* American Society of Anesthesiology status 1-2-3
* Able to comprehend and sign informed consent.
* If age \<18 years: parent or legal representative able to comprehend and sign informed conse…
Contacts