En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.
Recruiting
Observational Study
Spinal MetastasesSpinal TumorRadiotherapyMalignant Bone TumorSurgery
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 75
Sex
Any
Study type
Observational
Participants needed
182 (estimated)
Sponsor
Shanghai Changzheng Hospital · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The purpose of this clinical trial is to explore the impact of En bloc surgery and separation surgery combined with radiation therapy on the prognosis and survival of patients with spinal oligometastatic cancer, describe the clinical results, and optimize future treatment goals
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 1\) Be able to sign written informed consent.
* 2\) Age range from 18 to 75 years old, regardless of gender.
* 3\) Within conservative treatment, the patient still has uncontrollable pain, metastatic cancer lesions that still progress, spinal instability/potential instability,…
Inclusion Criteria:
* 1\) Be able to sign written informed consent.
* 2\) Age range from 18 to 75 years old, regardless of gender.
* 3\) Within conservative treatment, the patient still has uncontrollable pain, metastatic cancer lesions that still progress, spinal instability/potential instability, or symptoms of spinal cord/nerve compression.
* 4\) After the patient underwent Positron Emission Tomography-Computed Tomography (PET-CT) examination, it was indicated that there were no more than 3 metastatic organs and no more than 5 metastatic lesions in the whole body of cancer. Among them, there was at least 1 spinal metastasis and at most 5 spinal metastases.
* 5\) Imaging examinations (enhanced MRI, enhanced CT, X-ray) indicate the presence of spinal metastasis.
* 6\) The expected survival period is ≥ 6 months.
* 7)No other surgical contraindications
Exclusion Criteria:
* 1\) Primary tumors of the spine or multiple tumors of the body, with\>3 metastatic organs and\>5 metastatic sites.
* 2\) Previously underwent spinal surgery, or received radiotherapy for the responsible segment of this treatment.
* 3\) Severe heart, lung, liver, kidney or other diseases affecting the surgery.
* 4\) Having cognitive impairment, sensory aphasia, and inability to understand basic instructions.
* 5\) Participated in clinical trials of other drugs or medical devices within 3 months prior to enrollment.
* 6\) Infectious diseases.
* 7\) Refuse to follow up or participate.
* 8\) The researchers determine that the patients are not suitable for enrollment this clinical trail.
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