Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty
Recruiting
Phase 2
Interventional Study
Chronic Pain
Knee Pain Chronic
Post Operative Pain
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 400 (estimated)
- Sponsor
- University Health Network, Toronto · Other
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About This Trial
Phase II Multicentre, pilot, parallel-group, blinded, 1:1 randomized controlled trial to determine the feasibility of conducting a larger definitive trail of using vitamin C to reduce persistent pain in patients undergoing total knee arthroplasty surgery.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients \>18 years old
* Undergoing a unilateral or bilateral primary total knee arthroplasty for advanced osteoarthritis of the knee
Exclusion Criteria:
* TKA for infection (septic joint), fracture, ankylosing spondylitis, lupus, or psoriatic arthritis
* History of kidney …
Contacts