Androgens and NAFLD Longitudinal Cohort Study
Recruiting
Observational Study
PCOS
NAFLD
NASH
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 42
- Sex
- Female
- Study type
- Observational
- Participants needed
- 150 (estimated)
- Sponsor
- University of California, San Francisco · Other
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About This Trial
The researchers want to learn how androgens, a type of sex hormone, might affect nonalcoholic fatty liver (NAFLD) in young women over time. NAFLD happens when fat builds up in the liver which can cause damage to the liver such as inflammation or scarring.
Young women with a condition called polycystic ovary syndrome (PCOS) have a high risk for NAFLD, and they often have high androgen levels too. …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Metabolic associated steatohepatitis (MASH) (formerly NASH)
* PCOS
* Non-PCOS
Exclusion Criteria:
* High levels of alcohol use (more than 7 drinks a week)
* Current pregnancy
* Other causes of hepatic steatosis
* Weight loss of more than 10% body weight in the last 6 months