Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration
Recruiting
N/A
Interventional Study
Liver Dysfunction
Liver Metastasis Colon Cancer
Liver Regeneration
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 70 (estimated)
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre · Other
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About This Trial
The primary objective of this interventional study is determine if the future liver remnant can be optimized by improving liver function pre-operatively in patients who are scheduled for major hepatectomy. The main questions it aims to answer are:
1. Does high-dose insulin therapy improve liver function in the pre-operative setting?
2. What is the effect of high-dose insulin therapy on liver func…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age \> 18 years old
* Candidate for major liver resection
* Resectable colorectal liver metastasis
Exclusion Criteria:
* Inability to give consent
* Type 1 diabetes mellitus
* Uncontrolled blood glucose levels (fasting level \> 10 mmol/L)
* Unresectable colorectal liver meta…
Contacts