Infection Prophylaxis in Total Joint Replacement

Recruiting Phase 3 Interventional Study
Periprosthetic Joint Infection
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Prevention
Participants needed
21,006 (estimated)
Sponsor
Hamilton Health Sciences Corporation · Other
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About This Trial
Osteoarthritis (OA) is the most common cause of disability in older adults worldwide affecting 7% of the global population, or more than 500 million people globally. Total joint replacements (TJR) can help bring relief to those with osteoarthritis when other treatment options are no longer helpful. Infection is the main reason hip and knee replacements "fail". Failure leads to repeat surgeries tha…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Patients 18 years of age or older. 2. Undergoing primary or aseptic revision TJR. 3. No contraindications to study interventions. 4. Informed consent (participant or substitute decision maker) obtained and willing to comply with the protocol. Exclusion Criteria: 1. Received…
Contacts

Lindsay Maharaj, MSc

905-521-2100

maharajli@hhsc.ca

CONTACT