A 5-year Natural History Study in LAMA2-related Muscular Dystrophy and SELENON-related Myopathy.

Recruiting Observational Study
LAMA2-related Muscular Dystrophy SELENON-related Myopathy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
1 Day – 100
Sex
Any
Study type
Observational
Participants needed
40 (estimated)
Sponsor
Radboud University Medical Center · Other
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About This Trial
SELENON-related myopathy (SELENON-RM) and LAMA2-related muscular dystrophy (LAMA2-MD) are congenital neuromuscular disorders presenting with slowly, progressive axial muscle weakness, spinal rigidity, scoliosis and respiratory insufficiency. Currently, no curative treatment options exist, yet promising preclinical trials are ongoing. Clinical trials are expected to start within 5 years. Natural hi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Willing and able to complete (part of) the measurement protocol at the Radboudumc, Nijmegen. If patients do not wish or not able to visit our neuromuscular center, they are offered to participate in our study through home visits. * Genetic conformation of LAMA2-related muscula…
Contacts

Ilse de Laat

+31611469112

ilse.delaat@radboudumc.nl

CONTACT

Nicol Voermans, MD PhD

+31650155770

nicol.voermans@radboudumc.nl

CONTACT