Effect of Ketamine on Intraoperative Motor Evoked Potentials
Recruiting
Phase 3
Interventional Study
Spine Fusion
Spine Tumor
Spinal Stenosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 100
- Sex
- Any
- Trial phase
- Phase 3
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 20 (estimated)
- Sponsor
- University of California, San Francisco · Other
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About This Trial
The goal of this clinical trial is to learn about the effect of ketamine on intraoperative motor evoked potentials in adult patients undergoing thoracolumbar spinal fusions. Participants will undergo a standard anesthetic. In addition to the standard anesthetic, the patients will be administered increasing doses of ketamine with motor-evoked potentials being measured at each dose, to assess any im…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adult patients (\>18 years of age) undergoing posterior spinal fusions.
Exclusion Criteria:
* Sensitivity or allergy to ketamine.
* Schizophrenia or other psychotic conditions
* Uncontrolled hypertension with systolic blood pressure greater than 180 mmHg
* Myocardial Infarct…
Contacts