Bruton Tyrosine Kinase Inhibitors for B-cell Malignancies

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

Recruiting Observational Study
Chronic Lymphocytic Leukemia Hematopoietic and Lymphoid System Neoplasm Mantle Cell Lymphoma Marginal Zone Lymphoma Waldenstrom Macroglobulinemia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for

This trial is looking for patients with certain blood cancers who are starting treatment with specific medications called Bruton tyrosine kinase inhibitors. Participants will be monitored for changes in their blood pressure during the treatment.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have chronic lymphocytic leukemia
  • I have mantle cell lymphoma
  • I have Waldenstrom macroglobulinemia
  • I have marginal zone lymphoma
  • I am planning to begin treatment with Bruton tyrosine kinase inhibitors
  • I am willing to return to the Mayo Clinic for follow-up

You may not be able to join if

  • I have known central nervous system involvement of my B-cell malignancy

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

This study evaluates the incidence and management of new and worsening high blood pressure in patients with B-cell cancers on BTKi treatment.

Trial Locations
Loading…

Loading trial locations…

Eligibility Criteria
Inclusion Criteria: * Patients with chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), Waldenstrom macroglobulinemia (WM), and marginal zone lymphoma (MZL), planned to begin Bruton tyrosine kinase inhibitors (BTKi) treatment or who will start a new BTKi agent after a 5-day wash out per…
Contacts

Clinical Trials Referral Office

855-776-0015

mayocliniccancerstudies@mayo.edu

CONTACT