Sleep and Neuropathic Pain - Intervention Study on Pregabalin

Recruiting N/A Interventional Study
Neuropathic Pain Insomnia Sleep Disorder
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
Helsinki University Central Hospital · Other
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About This Trial
The goal of this clinical study is to study sleep and its microstructure in neuropathic pain patients who have or who do not have a clinically significant sleep disturbance, before and during (after 1-month stabile dosage) pregabalin treatment. To find out whether reduced pain by pregabalin associates with improved sleep quality; to study, using resting state fMRI, brain network connectivity and t…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Chronic (duration \> 3 months) painful peripheral neuropathy * Pain moderate to severe (NRS ≥ 4/10) during the past week Exclusion Criteria: * psychotic depression, clinically significant bipolar disorder * contraindication for performing brain fMRI (metal in the body etc)
Contacts

Hanna Harno, PhD

+358503427375

hanna.harno@hus.fi

CONTACT

Eija Kalso, PhD

+358504270609

eija.kalso@helsinki.fi

CONTACT