Perioperative Dexmedetomidine on Postoperative Delirium in Patients With Brain Tumors
Recruiting
N/A
Interventional Study
Postoperative Delirium
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 366 (estimated)
- Sponsor
- Beijing Tiantan Hospital · Other
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About This Trial
Neurosurgery is a risk factor for delirium. Dexmedetomidine might reduce delirium by reducing neuroinflammation, improving postoperative analgesia and sleep quality. The the primary hypothesis is that perioperative administration of dexmedetomidine can reduce the incidence of postoperative delirium
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients with temporal glioma scheduled for a elective craniotomy
* Age ≥18 years
* Obtain written informed consent.
Exclusion Criteria:
* Patients with severe preoperative cognitive impairment
* History of traumatic brain injury or previous neurosurgery
* History of psychot…
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