Morphine vs Oxycodone for Post-Surgery Pain Control
Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone
Recruiting
Phase 4
Interventional Study
Patient-Controlled Analgesia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 6 – 18
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 690 (estimated)
- Sponsor
- Murdoch Childrens Research Institute · Other
Who this trial is looking for
This trial is looking for young patients aged 6 to 18 who need pain relief after surgery. Participants will be assigned to receive either morphine or oxycodone and will get regular medical care as part of their treatment.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 6 and 18 years old
- I am having surgery
- I am suitable for patient-controlled analgesia (PCA)
- My anaesthetist believes I can use morphine or oxycodone
- My ASA score is between 1 and 3
- My parent or guardian has given consent for me to join
You may not be able to join if
- I am allergic to morphine or oxycodone
- I cannot use the PCA device due to disability
- My ASA score is 4 or higher
- My parent or guardian cannot give consent for me to join
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
POPCORN trial will compare the side effects and effectiveness of Morphine versus Oxycodone medication when prescribed for use as patient controlled analgesia (PCA) for pain relief for paediatric patients after-surgery. This trial is embedded into routine patient care using the hospital electronic medical record (EMR). Participants will be randomly assigned to either medication after they enrol in …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Postoperative patients who are appropriate for a PCA including those aged 6 and above and up to age 18 years.
* Those deemed appropriate for either morphine or oxycodone by their treating anaesthetist.
* American Society of Anaesthesiologists (ASA) score 1-3 inclusive
* Those …
Contacts