MicroRNAs as Biomarkers for Obstructive Sleep Apnea
Recruiting
Observational Study
Obstructive Sleep Apnea
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Observational
- Participants needed
- 500 (estimated)
- Sponsor
- University of Pennsylvania · Other
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About This Trial
Although obstructive sleep apnea (OSA) is a common disorder, there are no blood biomarkers for identification and management of these patients. This project will study microRNAs in order to develop and validate blood biomarkers that are specific to OSA, useful for identification of cases with OSA, reflective of efficacy of therapy, and able to predict blood pressure response to treatment of OSA.
Trial Locations
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Eligibility Criteria
Inclusion Criteria for Cases:
* age 18-75 years
* moderate-severe OSA (defined as AHI ≥15 events/hour)
* willing to accept PAP therapy
Inclusion Criteria for Controls:
* age 18-75 years
* no OSA (defined as AHI \<5 events/hour)
Exclusion Criteria for Cases:
* current use of PAP or other OSA tre…
Contacts