Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients

Recruiting Observational Study
Acute Respiratory Failure Critical Illness
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
200 (estimated)
Sponsor
The Institute of Molecular and Translational Medicine, Czech Republic · Other
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About This Trial
Mechanically ventilated intensive care patients will be sampled for a small amount of exhaled breath condensate from the ventilator circuit and for venous blood. Proteomic analysis of the exhaled breath condensate will be performed using mass spectrometry and in the blood sample, corresponding changes in the DNA, RNA, proteins, and metabolites will be studied. Resulting profiles will be correlate…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Intensive care setting Mechanical ventilation Ventilator/ventilator circuit technically suitable for sampling of exhaled breath condensate Exclusion Criteria: Mechanical ventilation challenging to the extent that the insertion of the sampling kit into the ventilator circuit wo…
Contacts

Emil Berta, MD PhD

+420585632111

e.berta@upol.cz

CONTACT

Karel Axmann, MD

+420588445356

karel.axmann@fnol.cz

CONTACT