Overfeeding Induced Fat-tissue Stimulation
Recruiting
N/A
Interventional Study
Lipid-induced Insulin Resistance
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 40
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 32 (estimated)
- Sponsor
- German Diabetes Center · Other
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About This Trial
Type 2 diabetes is the most common metabolic disease worldwide, characterized by hyperglycemia, decreased whole body insulin sensitivity, and white adipose tissue (WAT) dysfunction. A key factor in its development is chronic overnutrition, usually with a high-fat diet (HFD), leading to disturbances of glucose and lipid metabolism. However, the mechanism of short-term HFD-induced tissue-specific in…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age between 18 and 40 years
* BMI \< 29 kg/m2
* Sport inactive (\<1x /week)
* Capacity to consent
Exclusion Criteria:
* Diabetes mellitus disease
* Acute coronary heart syndrome (myocardial infarction, unstable angina pectoris, stroke or transient ischemic attack in the last…
Contacts