No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
16 – 35
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
210 (estimated)
Sponsor
University of British Columbia · Other
Who this trial is looking for
This trial is looking for young people between 16 and 35 years old who have had ACL reconstruction surgery. Participants will either take part in an education and exercise program or a minimal intervention to see which is more effective for knee health.
Are You a Good Fit for This Trial?
You may be able to join if
I live in British Columbia, Canada
I am 16 to 35 years old
I had my first ACL reconstruction surgery 9 to 36 months ago
I am not receiving knee care from a provider
I have daily access to email and a computer with internet
I am willing to wear an activity tracker
I scored below 79 points on the KOOS4 assessment
You may not be able to join if
I cannot communicate in English
I have had a knee injury that caused me to miss physical activity before my ACL tear
I have been diagnosed with knee osteoarthritis by a doctor
I have inflammatory arthritis or another serious health condition
I have had any lower limb injury or surgery in the past 6 months
I am currently pregnant
I have a pacemaker or other implanted medical device
I have had an MRI exclusion due to metal fragments or certain recent procedures
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
By 2040, 25% of Canadians will have osteoarthritis, a disabling joint condition. Most people think osteoarthritis only affects older adults, but 50% of the 700,000 Canadian youth who hurt their knee playing sports annually will develop osteoarthritis by 40 years of age. These young people with old knees face knee pain and disability for much of their adult lives, interfering with parenting, work, …
By 2040, 25% of Canadians will have osteoarthritis, a disabling joint condition. Most people think osteoarthritis only affects older adults, but 50% of the 700,000 Canadian youth who hurt their knee playing sports annually will develop osteoarthritis by 40 years of age. These young people with old knees face knee pain and disability for much of their adult lives, interfering with parenting, work, and recreation. Yet, most do not know about osteoarthritis or how to reduce their risk.
In this clinical trial, people who have torn the Anterior Cruciate ligament in their knee and had reconstruction surgery 9-36 months previously will be randomized to receive either a 6-month virtual education and exercise therapy program called Stop OsteoARthritis (SOAR) or a minimal intervention control program. Researchers will test if those who received the SOAR program have larger gains in knee health, including pain, symptoms, function, and quality of life at 6, 12, and 24 months. Researchers will also use MRIs (baseline and 24 months) to assess how the SOAR program influences knee cartilage degeneration and its cost-effectiveness.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Currently live in British Columbia, Canada
* 16-35 years of age (inclusive)
* 9-36-months past a first-time ACLR performed ≤12-months of first-time ACL tear
* Currently not receiving knee care from a health or fitness provider and have no scheduled surgical procedures (any par…
Inclusion Criteria:
* Currently live in British Columbia, Canada
* 16-35 years of age (inclusive)
* 9-36-months past a first-time ACLR performed ≤12-months of first-time ACL tear
* Currently not receiving knee care from a health or fitness provider and have no scheduled surgical procedures (any part of the body) that would interfere with exercise during the study.
* Score below a KOOS4 PASS (\<79 points)
* Have daily access to an email address and a computer with internet
* Are willing to wear an activity tracker during the study
Exclusion Criteria:
* Inability to communicate in English
* No medical attention (healthcare provider) time-loss (missed physical activity, sport or work ≥2 occasions) injury to the ACLR knee before the ACL tear
* Previous physician diagnosis of index knee osteoarthritis
* Inflammatory arthritis or other systemic condition
* Lower limb injury, surgery, or intra-articular injection in the past 6-months
* Current pregnancy
* MRI contraindications (i.e., Weight over 400 lbs (MRI machine limit); Pacemaker or any other implanted medical device (i.e., wires, defibrillator, artificial heart valve, an electronic device like a drug infusion pump, electrical stimulator for nerves or bones, coil, catheter, or filter in any blood vessel, ear or eye implant, or stainless steel intrauterine device (IUD); Brain or ferromagnetic aneurysm clip; any other metallic prostheses or shrapnel, bullets, or other metal fragments; injury where a piece of metal lodged in the eye or orbit, or; surgery, medical procedure or tattoos (including tattooed eyeliner) in the last 6 weeks).
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