Risk Prediction Model for Exacerbating Phenotype in Patients With Chronic Obstructive Pulmonary Disease
Recruiting
Observational Study
Chronic Obstructive Pulmonary Disease Severe
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 40 – 85
- Sex
- Any
- Study type
- Observational
- Participants needed
- 365 (estimated)
- Sponsor
- Li An · Other
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About This Trial
This study is planned to be conducted based on the cohort of patients with severe chronic obstructive pulmonary disease in our hospital. Based on gut microbiota, random forest was used to search for potential diagnostic biomarkers in patients with frequent acute exacerbation and controls with non frequent acute exacerbation; Construct a frequent acute exacerbation risk prediction model using rando…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Patients who meet the diagnostic criteria for COPD of the global initiative for chronic obstructive lung diseases (GOLD 2022) and GOLD grading Ⅲ - Ⅳ (FEV1/FVC\<70%, FEV1% predicted value ≤ 50% after Bronchiectasis)
2. Age\>40 years old
3. COPD stable for more than 4 wee…
Contacts