Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases

Recruiting N/A Interventional Study
Colorectal Cancer Colorectal Neoplasms Malignant Liver Metastasis Colon Cancer Liver Metastases
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 80
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
Oslo University Hospital · Other
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About This Trial
The SYLMET Trial is a randomized trial to compare simultaneous and two-staged resection of primary colorectal and synchronous liver metastases. This is an investigator-initiated, multicentre, randomized controlled trial to assess complications (primary endpoint), survival, cost-effectiveness, and quality of life (secondary endpoints).This trial will include patients with resectable primary tumour …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 18-80 years old. * Both CRC and liver metastases in situ at time of evaluation. * Resectable primary tumor in the colon or upper rectum. * Less than 5 liver metastases, evaluated by the multidisciplinary tumor board meeting as possible to treat with surgical resection and/…
Contacts

Sheraz Yaqub, MD PhD

+47-23073296

shya@ous-hf.no

CONTACT

Frida B Hansen

frbhan@ous-hf.no

CONTACT