Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty
Recruiting
N/A
Interventional Study
Postoperative Bleeding
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 210 (estimated)
- Sponsor
- St. Mary's Research Center, Canada · Other
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About This Trial
Tranexamic acid (TXA) is an anti-fibrinolytic agent developed in the 1960s that has been safely used to reduce blood loss, transfusion rates and bleeding-associated mortality in trauma, obstetrics and orthopedic surgery, including hip fracture care and arthroplasty.
The efficacy and safety profile of TXA has been extensively studied in numerous clinical trials and observational studies. Its wide …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
° All adults undergoing primary TKA and THA at St-Mary's Hospital
Exclusion Criteria:
* Age \< 18 years
* Known hypersensitivity or allergy to TXA
* Previous history of thromboembolic disease
* Active malignancy (all current cancers other than local skin cancer)
* Significant …
Contacts