Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis
Recruiting
Observational Study
Cystic Fibrosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 13 – 20
- Sex
- Any
- Study type
- Observational
- Participants needed
- 36 (estimated)
- Sponsor
- Massachusetts General Hospital · Other
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About This Trial
The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls. The investigators will also be assessing their bone mineral density via other imaging modalities, including dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT). This longitudin…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 13-20 years old
* Cystic fibrosis with pancreatic insufficiency
* Must have a stable treatment regimen, including CFTR modulator usage unchanged for the prior three months
* Liver transplant recipients will be eligible, as long as they are at least 1 year post-transplant and a…
Contacts