Predicting Treatment Outcomes in Refractory Constipation Through Brain Connectivity Evaluation
Recruiting
Observational Study
Constipation - Functional
Refractory Constipation
Fluoxetine
fMRI
Brain Connectivity
Treatment Efficacy
Somatic Symptom
Mental Symptom
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 45
- Sex
- Any
- Study type
- Observational
- Participants needed
- 150 (estimated)
- Sponsor
- Xijing Hospital of Digestive Diseases · Other
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About This Trial
The goal of this observational study is to identify the characteristics of brain functional connectivity in refractory constipation and fluoxetine-sensitive patients. The main questions it aims to answer are:
* Investigating the alterations in brain functional connectivity in patients with refractory constipation and fluoxetine-sensitive patients
* Assessing the predictive value of brain function…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18≤ age ≤ 45 years old
* Right-handed
* Patients diagnosed as functional constipation according to the Rome IV criteria
* Informed consent of patients
Exclusion Criteria:
* Complicated with gastrointestinal organic disease or significant functional abnormalities (tuberculosi…
Contacts