Meal Size Testing for Healthy Adults

Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose

Recruiting N/A Interventional Study
Obesity Healthy Volunteer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 99
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
79 (estimated)
Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · NIH
Who this trial is looking for

This trial is looking for healthy adults aged 18 and older to see how different meal sizes affect blood sugar levels. Participants will attend 3 or 4 visits over 8 weeks where they will complete tests and consume meals of different sizes.

Are You a Good Fit for This Trial?
Must not be taking Acetaminophen
Rules you out Type 1 diabetesType 2 diabetesSignificant anemiaGastrointestinal diseasesAlcohol abuse

You may be able to join if

  • I am at least 18 years old
  • I am healthy according to a medical exam
  • I can provide signed consent
  • I agree to follow the study guidelines

You may not be able to join if

  • I have diabetes or high fasting blood sugar
  • I am currently pregnant or breastfeeding
  • I have a significant blood disorder or anemia
  • I have a history of gastrointestinal diseases
  • I abuse alcohol
  • I cannot stop taking high doses of acetaminophen
  • I have a food allergy that prevents me from consuming the meals
  • I have a condition that could affect my safety in the study

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial
Background: Researchers use mixed meal tolerance tests (MMTTs) to look at how people s bodies respond to eating a meal. However, researchers do not agree on how to decide the number of calories to give in each meal. Some use fixed meals, which are the same size for everyone, and some use adjusted meals, based on the size of the person s body. Researchers want to know which MMTT is best to use for…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Provision of signed and dated informed consent form. * Agreement to adhere to Lifestyle Considerations throughout study duration. * Males and females; Age \>= 18year…
Contacts

Susanne M Votruba, Ph.D.

(301) 827-3521

votrubas@niddk.nih.gov

CONTACT