Threonine Requirement in Adults >60 Years of Age

Recruiting N/A Interventional Study
Healthy Aging
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
60 – 90
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
40 (estimated)
Sponsor
The Hospital for Sick Children · Other
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About This Trial
Threonine is an essential amino acid and must be obtained from the diet. The body's capacity to maintain adequate mucin synthesis is directly related to the bioavailability of certain amino acids, including threonine, serine and proline (1). Moreover, the rate of mucin synthesis has been demonstrated to be directly related to the availability of dietary threonine in healthy rats (2) and piglets (3…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Consent provided * Aged 60 to 90 years old * In good general health as evidenced by medical history, physical health and blood draw * Fasting blood glucose, hemoglobin A1c (HbA1c), urea, creatinine * Willingness to participate in the study. * BMI \<30 kg/m2. Exclusion Criteri…
Contacts

Alyssa Paoletti, PhD, MSc

4164207076

alyssa..paoletti@sickkids.ca

CONTACT

Mahroukh Rafii, BSc

416 813 7454

mahroukh.rafii@sickkids.ca

CONTACT