Blood Testing for Triple-Negative Breast Cancer Treatment

CtDNA Based MRD Testing for NAC Monitoring in TNBC

Recruiting Observational Study
TNBC - Triple-Negative Breast Cancer Minimal Residual Disease
No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Female
Study type
Observational
Participants needed
422 (estimated)
Sponsor
Personalis Inc. · Industry
Who this trial is looking for

This trial is looking for patients with early-stage triple-negative breast cancer who are starting treatment with chemotherapy. Participants will provide blood samples to help understand the effectiveness of a new testing method during their treatment.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with triple-negative breast cancer.
  • I have early-stage breast cancer and will start chemotherapy soon.
  • I am at least 18 years old.
  • I am willing to provide blood samples before and during treatment.
  • I am willing to sign a consent form for the trial.
  • I have available biopsy tissue.

You may not be able to join if

  • I have stage IV breast cancer.
  • I am currently being treated for another type of cancer.
  • I have had another primary cancer in the last 5 years.
  • I have had a bone marrow or organ transplant.
  • I have had a blood transfusion in the last two weeks.
  • I have already started other chemotherapy for my breast cancer.
  • I am pregnant.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

A prospective, multicenter, observational study to evaluate the correlation of Molecular Residual Disease (MRD) detection using circulating tumor DNA guided test to pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in stage I-III triple negative breast cancer (TNBC). Results from this study aim to improve MRD detection and disease outcomes for future patients.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Have histologically documented TNBC (defined as ER expression ≤10% by IHC, PR expression≤10% by IHC and HER2 0 or 1+ by IHC or FISH ratio \<2 or HER2 gene copy number of \<6). 2. Early-stage breast cancer (stage I-III) and scheduled to undergo NAC treatment with curative inte…
Contacts

Soumya Chappidi

484-704-2599

schappidi@criteriuminc.com

CONTACT

Julee Hartwell

607-651-6273

jhartwell@criteriuminc.com

CONTACT