Cortical Electrophysiology of Response Inhibition in Parkinson's Disease

Recruiting Phase 4 Interventional Study
Parkinson Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
45 – 75
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Basic Science
Participants needed
80 (estimated)
Sponsor
Emory University · Other
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About This Trial
Patients with Parkinson's Disease will be studied before, during, and after a deep brain stimulation implantation procedure to see if the stimulation location and the size of the electrical field produced by subthalamic nucleus (STN) DBS determine the degree to which DBS engages circuits that involve prefrontal cortex executive functions, and therefore have a direct impact on the patient's ability…
Trial Locations
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Eligibility Criteria
Inclusion Criteria for Persons with Parkinson's Disease for Aim 1: * diagnosis of idiopathic Parkinson's disease (PD) * Hoehn and Yahr (H\&Y) stage 2-4 (off medication) Exclusion Criteria for Persons with Parkinson's Disease for Aim 1: * severe tremor at rest or severe dyskinesia which would caus…
Contacts

Jonna Seppa

404-727-1509

jonna.k.seppa@emory.edu

CONTACT

Svjetlana Miocinovic, MD, PhD

404-712-9065

CONTACT