Energetics and Glutamate in Schizophrenia
Recruiting
Observational Study
Schizophrenia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Observational
- Participants needed
- 75 (estimated)
- Sponsor
- King's College London · Other
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Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The goal of this case-control study is to compare brain glutamate, glucose utilisation, lactate production and brain activity in healthy volunteers and people with a diagnosis of schizophrenia.
It investigates the following main questions:
Whether, compared to healthy volunteers, participants with schizophrenia show:
1. reduction in brain glucose utilisation
2. increased brain lactate
3. greate…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Healthy volunteer group:
1\. No history of psychiatric illness, as assessed on the Mini neuropsychiatric Interview (MINI).
Treatment responsive schizophrenia group:
1. Meeting ICD-11 criteria for schizophrenia (F20)
2. Meeting symptomatic consensus criteria for remission, def…
Contacts