Hybrid Closed Loop Pump for Type 1 Diabetes

Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes

Recruiting N/A Interventional Study
Diabetes Mellitus, Type 1 Diabetes Complications
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 75
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
140 (estimated)
Sponsor
Boston Medical Center · Other
Who this trial is looking for

This trial is looking for adults with type 1 diabetes who want to try a new insulin delivery system. Participants will use a hybrid closed loop pump for 9 months and share their experiences and health results.

Are You a Good Fit for This Trial?
Must not be taking HydroxyureaSGLT-2 inhibitorsSulfonylureas
Rules you out Extreme visual impairmentExtreme hearing impairmentCognitive concernsActive cancer treatment

You may be able to join if

  • I have type 1 diabetes.
  • I have been using multiple daily injections for at least 6 months.
  • My A1c level is 7.0% or higher.
  • I can understand, speak, and read English.
  • I am willing to use certain types of insulin.
  • I take at least 10 units of insulin each day.
  • I can follow the study instructions.

You may not be able to join if

  • I currently use an insulin pump.
  • I cannot provide informed consent.
  • I am taking hydroxyurea.
  • I am taking SGLT-2 inhibitors or sulfonylureas.
  • I have a tape allergy or skin issue that prevents pump use.
  • I am pregnant or planning to become pregnant.
  • I am currently on renal dialysis.
  • I have a significant psychiatric diagnosis or substance abuse issue.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial
Minoritized individuals with type 1 diabetes (T1D) have approximately 2% higher average A1c levels and twice the rate of hospitalizations, complications, and mortality as their white counterparts. However, the efficacy trials establishing the benefits of hybrid closed loop (HCL) pump therapy in T1D have been in more socially advantaged and predominantly non-Hispanic white patients. Use of this tec…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of T1D for at least 12 months, on MDI for at least 6 months; * A1c ≥7.0% with no upper limit at screening (The investigator will consider the participant A1c level, compliance with current diabetes management, and prior acute diabetic complications. For this…
Contacts

Howard Wolpert, MD

617-285-9096

howard.wolpert@bmc.org

CONTACT

Astrid Atakov Castillo, BA

617-638-5906

Astrid.AtakovCastillo@bmc.org

CONTACT